MyBioSource.com's Mouse Anti-DST monoclonal Antibody is a Mouse monoclonal antibody. The Mouse Anti-DST monoclonal Antibody was generated using DST, and dystonin as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: ELISA.
Description
This gene encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been known that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration